Kidney live donor program

Methodist Transplant Institute at Methodist Hospital Specialty and Transplant is a national leader in exchange transplantation with a team solely dedicated to transplanting patients with living donors who are not a match. Methodist Transplant Institute has a very large database with hundreds of incompatible recipient/donor pairs. Over 250 patients have benefitted from this program.

• Incompatible exchange program: Recipients may have a willing living donor that cannot donate because they are not a match due to incompatible blood types or due to the recipient antibodies. A recipient/donor pair that is willing to participate in this program would be placed in a database to potentially find another recipient/donor pair that could be a compatible match for each other. It can be very difficult to find a suitable exchange pair and the wait can be long. You will be contacted by the exchange team when a potential match is found.
• Compatible exchange program: Another type of exchange program involves exchanging recipient/donor pairs that are “compatible,” meaning they are not sensitized and have compatible blood types. Research has shown that the age of the donor kidney is a strong predictor of long term kidney function. This Kidney Paired Donor Exchange Program offers patients with older compatible kidney donors the opportunity to exchange donors with recipients that have a younger donor who is not compatible with them.In this example, a recipient has a chance to receive a kidney from a younger donor while the other recipient with an incompatible donor is able to receive a living donor kidney transplant from a compatible donor.

We have a large in-house database designed to match donor/recipient pairs managed by a dedicated team of immunologists, physicians and transplant coordinators. Paired kidney donation is a step in reducing the time spent on the transplant waiting list, and increases access to organs for all kidney transplant candidates.

Please call the live donor hot line at (210) 575-GIVE (4483) or (800) 888-0402 if you think you might be a candidate for an incompatible transplant.

At one time, patients who could not find a compatible donor were not considered for a living donor kidney transplant. With the blood type incompatible program, patients can receive a kidney from a living donor either through a treatment process to remove antibodies that could cause rejection or through the donor exchange program.

About 30 percent of patients who are waiting for a transplant have high antibody levels, usually from a previous transplant, blood transfusion or pregnancy. These antibodies can make it very difficult to find a donor match, resulting in long wait times on the list. Many of these patients have living donors, but because they have high antibody levels, they react to the donor’s cells and are not a match. Through the sensitized program, the recipient can undergo plasmapheresis treatments with intravenous medication to help remove these antibodies. Sometimes this takes several treatments. The antibody levels are checked to see if the treatments are successful in order to schedule the living donor kidney transplant. A second option for sensitized patients with living donors is the donor exchange program. The recipient/donor pair will be placed in the donor exchange program to find a suitable exchange pair which is an acceptable match.